Dante travels across a desolate, futuristic Spain in search of his girlfriend, Ula. He is pursued by a bloodthirsty, cybernetic Rottweiler.

Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West’s limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West’s experiments 13 years earlier.