When Maya, a headstrong little bee, and her best friend Willi, rescue an ant princess they find themselves in the middle of an epic bug battle that will take them to strange new worlds and test their friendship to its limits.

Karla, a young medical student, is trying to cure her brother, Blake, from a terminal sleep illness called Fatal Familial Insomnia, where you are unable to sleep until you die. On her quest to treat him, a more sinister reason for his condition is revealed.

Ethan, a sullen high-school student whose life is defined by what he hates, finds love with a blindly optimistic Christian girl Trinity, much to the annoyance of his angst-filled band mates and her evangelistic brethren.

When an overenthusiastic Maya accidentally embarrasses the Empress of Buzztropolis, she is forced to unite with a team of misfit bugs and compete in the Honey Games for a chance to save her hive.