Two brothers’ relationship strains when the younger one receives news of a strange inheritance complicating their competition for a mysterious young woman who arrives on their island. The entire family reaches a breaking point brought about by startling revelations about their mother’s fidelity, love, friendship and betrayal.

A young African American man, reeling from the tragic loss of his wife, travels to rural Maine to seek answers from his estranged mother-in-law, who is herself confronting guilt and grief over her daughter’s death.

In the year 2035, convict James Cole reluctantly volunteers to be sent back in time to discover the origin of a deadly virus that wiped out nearly all of the earth’s population and forced the survivors into underground communities. But when Cole is mistakenly sent to 1990 instead of 1996, he’s arrested and locked up in a mental hospital. There he meets psychiatrist Dr. Kathryn Railly, and patient Jeffrey Goines, the son of a famous virus expert, who may hold the key to the mysterious rogue group, the Army of the 12 Monkeys, thought to be responsible for unleashing the killer disease.

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A poor young woman is recruited by a friendly couple traveling in an RV into becoming part of the dark world of truck stop prostitution.

When her brother Bobby returns from World War II mentally damaged, Anna has to deal with her parents who don’t acknowledge her brother’s existence, who is now brought to a mental hospital. After his sudden death Anna begins to question her own sanity. Her gangster boyfriend Billy’s action pushes her further, she’s now convinced the only way she can be “cured” is to have a lobotomy.

The story of a broken family striving to stay together while a curse and the ghosts of a haunted house try to tear them apart.

Told from the points of view of both the Baltimore homicide and narcotics detectives and their targets, the series captures a universe in which the national war on drugs has become a permanent, self-sustaining bureaucracy, and distinctions between good and evil are routinely obliterated.