The down-and-out private detective Harry Angel is ordered, by a mysterious man named Louis Cyphre, to go on a mission to find a missing person. His routine failure soon leads to a bloody spar with himself as Harry Angel goes on a supernatural journey into his own soul.

A multi-layered satire of race relations in America. Live-action sequences of a prison break bracket the animated story of Brother Rabbit, Brother Bear, and Preacher Fox, who rise to the top of the crime ranks in Harlem by going up against a con-man, a racist cop, and the Mafia.

An “underground” cartoonist contends with life in the inner city, where various unsavory characters serve as inspiration for his artwork.