After a car wreck on the winding Mulholland Drive renders a woman amnesic, she and a perky Hollywood-hopeful search for clues and answers across Los Angeles in a twisting venture beyond dreams and reality.

Henry Spencer tries to survive his industrial environment, his angry girlfriend, and the unbearable screams of his newly born mutant child.

A reporter investigating the bizarre death of a woman who leaped from a building in flames finds herself mixed up in a cult of witches who are making her part of their sacrificial ceremony during the Christmas season.