Two married couples find only trouble and heartache as their complicated lives unfold. After 40 years of marriage, Alfie leaves his wife to pursue what he thinks is happiness with a call girl. His wife, Helena, reeling from abandonment, decides to follow the advice of a psychic. Sally, the daughter of Alfie and Helena, is unhappy in her marriage and develops a crush on her boss, while her husband, Roy, falls for a woman engaged to be married.

James is 17 and is pretty sure he is a psychopath. Alyssa, also 17, is the cool and moody new girl at school. The pair make a connection and she persuades him to embark on a darkly comedic road trip in search of her real father.