Even though Gennosuke and Oboro are from rival ninja villages, they are secretly in love. At an annual conference with the Lord, it is dictated that a competition–a fight to the death–will take place between the five best shinobi from each village. Gennosuke and Oboro’s love is made even more impossible when they each got picked as the leader of the five to represent their respective villages.

After being neglected by her mother, a little girl is taken in by her uncle and his transgender girlfriend, who create a loving home for her.

In the year 1868, three young men join the elite Shogitai division of the Shogunate. The Shogitai fights to the end and opposes the dismantling of the feudal military dictatorship known as the Bakufu system.

Mushi are beings in touch with the essence of life, far more basic and pure than normal living things. Most humans are incapable of perceiving Mushi and are oblivious to their existence, but there are a few who possess the ability to see and interact with Mushi. One such person is Ginko who travels from place to place to research Mushi and aid people suffering from problems caused by them.