The film follows a group of doctors, guards and violent prisoners on St Leonards Island in the north Atlantic, who must unite when a rampant disease threatens the high security units.

Steve Coogan and Rob Brydon embark on a road trip along the coast of Spain.

Ten strangers, drawn away from their normal lives to an isolated rock off the Devon coast. But as the mismatched group waits for the arrival of the hosts — the improbably named Mr. and Mrs. U.N. Owen — the weather sours and they find themselves cut off from civilization. Very soon, the guests, each struggling with their conscience, will start to die — one by one, according to the rules of the nursery rhyme ‘Ten Little Soldier Boys’ — a rhyme that hangs in every room of the house and ends with the most terrifying words of all: ‘… and then there were none.