An ex-Navy seal (Mehcad Brooks), his girlfriend (Serinda Swan) and their friends head out on a road trip to New Orleans. The group decides to stop at a roadside convenience store owned by Chopper (Sid Haig), who tells them the tale of Lockjaw, a fabled god-like creature who is half-man, half-alligator.
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Grave robbers supply a doctor with bodies to test on.
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