Four egocentric friends who run a neighborhood Irish pub in Philadelphia try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.

Self-proclaimed business expert, writer, director and comedian Nathan Fielder helps real small businesses turn a profit with marketing tactics that no ordinary consultant would dare to attempt. From driving foot traffic to an off-the-strip souvenir shop by using Hollywood flair and a Johnny Depp impersonator, to creating a rebate that can only be redeemed by climbing a mountain, to founding a coffee shop called “Dumb Starbucks,” Nathan has always gone to the limit to make his ideas come to life. With his unorthodox approach to problem solving, Nathan’s genuine efforts to do good often draw the real people he encounters into an experience far beyond what they signed up for.

Gossip Girl is an American teen drama television series based on the book series of the same name written by Cecily von Ziegesar. The series, created by Josh Schwartz and Stephanie Savage, originally ran on The CW for six seasons from September 19, 2007 to December 17, 2012. Narrated by the omniscient blogger “Gossip Girl,” voiced by Kristen Bell, the series revolves around the lives of privileged young adults on Manhattan’s Upper East Side in New York City.

The misadventures of a group of friends as they navigate the pitfalls of work, life and love in Manhattan.

An astronaut named Gary and his planet-destroying sidekick Mooncake embark on serialized journeys through space in order to unlock the mystery of “Final Space,” the last point in the universe, if it actually does exist.

An idealistic teen from rural Texas embarks on the adventure of a lifetime when she decides to leave behind starry nights for big city lights. Thrilled to be on her own and determined not to be intimidated by New York City, she accepts a job as nanny for a high-profile couple with four kids. Helping to keep her moral compass in check are Bertram, the family’s butler, and Tony, the building’s 20-year-old doorman.

Annie is a fat young woman who wants to change her life — but not her body. Annie is trying to start her career while juggling bad boyfriends, a sick parent, and a perfectionist boss.

A self-loathing, alcoholic writer attempts to repair his damaged relationships with his daughter and her mother while combating sex addiction, a budding drug problem, and the seeming inability to avoid making bad decisions.

Jessica Day is an offbeat and adorable girl in her late 20s who, after a bad breakup, moves in with three single guys. Goofy, positive, vulnerable and honest to a fault, Jess has faith in people, even when she shouldn’t. Although she’s dorky and awkward, she’s comfortable in her own skin. More prone to friendships with women, she’s not used to hanging with the boys—especially at home.

Harley Quinn has finally broken things off once and for all with the Joker and attempts to make it on her own as the criminal Queenpin of Gotham City.

A group of single parents lean on each other to help raise their 7-year-old kids and maintain some kind of personal lives outside of parenthood.

In the unreal world of Sacred Heart Hospital, John “J.D” Dorian learns the ways of medicine, friendship and life.